Steroid Responsive Encephalopathy Associated with Autoantibodies to Thyroperoxidase (STREAT), Presenting with Acute Stroke in a Young Female Patient

Abstract

A young lady in her mid-30s was presented with acute
ischemic stroke, associated with encephalopathy, in the
form of confusion and agitation. Clinical examination
demonstrated a profound tachycardia and thyroid swelling. Subsequent investigations revealed a multinodular
goiter, with elevated thyroperoxidase antibodies (TPO
Ab), on serology. Treatment with high-dose intravenous
corticosteroids leads to a prompt remission of the disease and related encephalopathy, and a dramatic clinical
improvement in the patient.