Endovascular treatment of basilar artery stenosis due to cerebral vasculopathy related to neurofibromatosis (NF1)

Abstract

Background—Cerebrovascular lesions are uncommon in neurofibromatosis type 1 (NF1).
Case Description—We report a case of 34-year-old man with NF1 who developed posterior circulation
stroke. Diffusion-weighted imaging showed acute infarcts in the right vertebra basilar artery territory. Digital subtraction angiography demonstrated significant stenosis of the basilar artery in the mid segment that
was identified as the etiology of the symptoms. The vertebral arteries were tortuous and the basilar artery
was ectatic. Subsequently endeavour resolute stent was placed across the lesion and post-procedure angiogram showed resolution of stenosis.
Conclusion—Selective stenotic involvement of the basilar artery with ectatic vertebrobasilar circulation
associated with NF1, which was successfully treated with endovascular method, was not been reported previously to our knowledge.