Complex Partial Epilepsy Associated with Temporal Lobe Developmental Venous Anomaly

Abstract

Background—Developmental venous anomalies (DVA) are found incidentally but sometimes patients
with these anomalies present with varying degrees of neurologic manifestations.
Objective—We report a patient with early onset complex partial epilepsy and associated DVA and discuss the natural history, neuroimaging and clinical characteristics, and management.
Case description—A 21-year-old man presented with a history of complex partial epilepsy with secondary generalization which started at the age of 4 years. An electroencephalogram (EEG) was performed
which demonstrated spike and wave discharges predominantly in the left frontotemporal region. A magnetic resonance imaging (MRI) was performed which demonstrated a linear flow void suggestive of a
DVA. The angiogram demonstrated DVA that connected with the left transverse venous sinus and an anastomotic vein between the straight sinus and the transverse venous sinus traversing the brain parenchyma.
He was started on carbamezipine for the treatment of complex partial seizures.
Conclusions—Temporal lobe DVA may be associated with complex partial seizures and can be diagnosed by MRI and angiographic findings.